Laboratory evaluation

Laboratory evaluation is mandatory with respect to HIV disease (9, 10) and thyroid disorders (ultrasensitive TSH assay) (11). Genetic testing is still experimental (12).

Autoantibody testing should be performed only if collagen vascular disease is supected on clinical grounds:
  • Anti-Scl-70 antibodies for progressive systemic sclerosis of diffuse type
  • Anti-centromere antibodies and for progressive systemic sclerosis of cutaneous limited type
  • Anti-U1-snRNP for mixed connective tissue disease
  • Anti-Jo-1 for polymyositis/dermatomyositis
  • Anti-dsDNA and anti-SM for systemic lupus erythematosus
  • Rheumatoid factor for rheumatoid arthritis.

Antinuclear antibodies are nonspecific since they are present in up to one third of the patients with PPH (3).

The presence of liver cirrhosis is suggested by hematologic abnormalities (macrocytosis, thrombocytopenia), electrophoresis (hypalbuminemia, hypergammaglobulinemia) and morphologic changes on ultrasound or computed tomography. Screening for possible chronic hepatitis (hepatitis S antigen, anti-HBc-IgM, anti-hepatitis C antibodies) may be indicated. Overall liver function can be assessed by determining factor V levels which reflects liver function even in anticoagulated patients. Elevated bilirubin levels greater than 36 µmol/l are indicative of severe cardiac cirrhosis and associated with poor survival after lung transplantation (13).

References
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SGPH-Symposium, 2. September 2010, Hotel Bristol in Genf:
"Hypertension artérielle pulmonaire: Comment ne pas passer à côté d’une maladie émergente?"  Mehr

 

Umfrage:

Helfen Sie uns, den Bereich "Patienten" weiter zu verbessern und Ihren Ansprüchen anzupassen indem Sie an unserer Umfrage teilnehmen.

 

Vereinsgründung:

Schweizer PH-Verein für Menschen mit pulmonaler Hypertonie gegründet. Pressemitteilung PDF

Next SSPH Workshop: October 28th, 2010
Haus der Universität in Berne, details will follow.

SSPH Workshop 2010: May 7-8, 2010

The SSPH workshop on May 7-8, 2010 in Lucerne did consist of an update of the website with the following topics:

  • Diagnosis
  • Treatment
  • Follow-up
  • Patients part

Many thanks to all the participants: The workshop from 7-8 May 2010 was a succesfull event, a lot of precious work has been done. Adaptations of the website content will soon be online.

 

4th international Congress of the SSPH

October 30 - 31, 2009



Link to the congress presentations as video streaming on swiss-webconferencing.ch .

Link to the congress photo-gallery

 

 



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