L-Arginine
Medical > Therapy > Specific treatments
L-Arginine
Theoretically, the oral supplementation of L-arginine, the precourser of NO, might improve hemodynamics in pulmonary hypertension. A small trial in 19 patients has demonstrated slight improvement in PAPm of 9 % and PVR of 16 % after one week of L-arginine 5 g/10 kg/weight/day and an improved exercise tolerance compared to placebo (Nagaya et al. 2001). However, is not clear if L-arginine might not have adverse long-term effects due to a potential increase in toxic NO radicals.
References:
Nagaya, N., M. Uematsu, H. Oya, et al. Short-term oral administration of L-arginine improves hemodynamics and exercise capacity in patients with precapillary pulmonary hypertension. Am J Respir Crit Care Med 163: 887-91., 2001
Back to > Medical > Therapy > Specific treatments
L-Arginine
Theoretically, the oral supplementation of L-arginine, the precourser of NO, might improve hemodynamics in pulmonary hypertension. A small trial in 19 patients has demonstrated slight improvement in PAPm of 9 % and PVR of 16 % after one week of L-arginine 5 g/10 kg/weight/day and an improved exercise tolerance compared to placebo (Nagaya et al. 2001). However, is not clear if L-arginine might not have adverse long-term effects due to a potential increase in toxic NO radicals.
References:
Nagaya, N., M. Uematsu, H. Oya, et al. Short-term oral administration of L-arginine improves hemodynamics and exercise capacity in patients with precapillary pulmonary hypertension. Am J Respir Crit Care Med 163: 887-91., 2001
Back to > Medical > Therapy > Specific treatments
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SSPH Research Prize 2012
Deadline for submission: April 30, 2012
Further information
Symposium "pulmonal-arterielle Hypertension im Kindesalter"
Donnerstag, 10. Mai 2012, 16.00-18.00, Bern
Further information:
5th International Congress of the Swiss Society of Pulmonary Hypertension (SSPH)
28.-29. September 2012, Thun, Congress Hotel Seepark Thun
Informationen: www.imk.ch/sgph2012
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