Excessive physical activity
Medical > Therapy > General measures
Excessive physical activity
Augmented tissue oxygen requirements during physical exercise causes the heart rate and stroke volume to increase. In healthy subjects during moderate exercise in supine position the average slope of mean pulmonary artery pressure/cardiac output relationship is approximately 1 mmHg for 1 l/min blood flow, which corresponds to a pulmonary artery pressure of 25 mmHg for a cardiac output of 20 l/min. In patients with pulmonary hypertension the slope of the pulmonary artery pressure/cardiac output relationship is steeper (> 2 mmHg/l min) because of elevated pulmonary vascular resistance and decreased compliance of the pulmonary vessels (Naeije, 1996). An exercise-induced abrupt excessive workload causes the right ventricle to dilate acutely, which in turn impairs left ventricular filling. This causes the systemic blood pressure to fall, which may lead to syncope. Patients with pulmonary hypertension should be aware of this potentially life-threatening complication and should avoid brisk and isometric physical exercise. However, this does not mean that patients with pulmonary hypertension can not take gentle physical exercise.
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Back to > Medical > Therapy > General measures
Excessive physical activity
Augmented tissue oxygen requirements during physical exercise causes the heart rate and stroke volume to increase. In healthy subjects during moderate exercise in supine position the average slope of mean pulmonary artery pressure/cardiac output relationship is approximately 1 mmHg for 1 l/min blood flow, which corresponds to a pulmonary artery pressure of 25 mmHg for a cardiac output of 20 l/min. In patients with pulmonary hypertension the slope of the pulmonary artery pressure/cardiac output relationship is steeper (> 2 mmHg/l min) because of elevated pulmonary vascular resistance and decreased compliance of the pulmonary vessels (Naeije, 1996). An exercise-induced abrupt excessive workload causes the right ventricle to dilate acutely, which in turn impairs left ventricular filling. This causes the systemic blood pressure to fall, which may lead to syncope. Patients with pulmonary hypertension should be aware of this potentially life-threatening complication and should avoid brisk and isometric physical exercise. However, this does not mean that patients with pulmonary hypertension can not take gentle physical exercise.
References
Back to > Medical > Therapy > General measures
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SSPH Research Prize 2012
Deadline for submission: April 30, 2012
Further information
Symposium "pulmonal-arterielle Hypertension im Kindesalter"
Donnerstag, 10. Mai 2012, 16.00-18.00, Bern
Further information:
5th International Congress of the Swiss Society of Pulmonary Hypertension (SSPH)
28.-29. September 2012, Thun, Congress Hotel Seepark Thun
Informationen: www.imk.ch/sgph2012
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