HIV therapy
Medical > Therapy > Basic treatments
HIV therapy
Pulmonary hypertension in patients with HIV infection affects the prognosis of these patients. In a Swiss cohort study, the median survival was 1.3 years in patients with pulmonary hypertension and 2.3 years in a matched control group (Opravil et al., 1997). Antiretroviral treatments affected significantly the development of pulmonary artery pressure. During a median follow-up of 1.3 years, pulmonary artery pressure increased by 19 mmHg in untreated patients, whereas it remained unchanged in those with an antiretroviral treatment (Opravil et al., 1997). Moreover, a recent cohort study on 1042 patients has shown that the incidence of HIV infection associated involvement of the pulmonary circulation and the heart decreased from 52 % to 19 % after the introduction of highly active antiretroviral therapy (Pugliese et al., 2000). Thus, there is indirect evidence that treatment of HIV infection improves pulmonary vascular resistance, and hence the prognosis of these patients.
References
Back to > Medical > Therapy > Basic treatments
HIV therapy
Pulmonary hypertension in patients with HIV infection affects the prognosis of these patients. In a Swiss cohort study, the median survival was 1.3 years in patients with pulmonary hypertension and 2.3 years in a matched control group (Opravil et al., 1997). Antiretroviral treatments affected significantly the development of pulmonary artery pressure. During a median follow-up of 1.3 years, pulmonary artery pressure increased by 19 mmHg in untreated patients, whereas it remained unchanged in those with an antiretroviral treatment (Opravil et al., 1997). Moreover, a recent cohort study on 1042 patients has shown that the incidence of HIV infection associated involvement of the pulmonary circulation and the heart decreased from 52 % to 19 % after the introduction of highly active antiretroviral therapy (Pugliese et al., 2000). Thus, there is indirect evidence that treatment of HIV infection improves pulmonary vascular resistance, and hence the prognosis of these patients.
References
Back to > Medical > Therapy > Basic treatments
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SSPH Research Prize 2012
Deadline for submission: April 30, 2012
Further information
Symposium "pulmonal-arterielle Hypertension im Kindesalter"
Donnerstag, 10. Mai 2012, 16.00-18.00, Bern
Further information:
5th International Congress of the Swiss Society of Pulmonary Hypertension (SSPH)
28.-29. September 2012, Thun, Congress Hotel Seepark Thun
Informationen: www.imk.ch/sgph2012
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